Article
Cystic fibrosis mutations impair the fertilization rate of epididymal sperm from men with congenital absence of the vas deferens.
Human reproduction (Oxford, England) - 1 Aug 1993
Patrizio P, Ord T, Silber S J, Asch R H
Abstract excerpt
One of the limiting factors for the successful treatment of male sterility due to congenital absence of the vas deferens (CAVD) is the low (< 20%) and extremely unpredictable rate of in-vitro fertilization of their epididymal spermatozoa. The recent demonstration that CAVD is a mild form of cysti...
Topics
- Adult
- Cystic Fibrosis
- Cystic Fibrosis Transmembrane Conductance Regulator
- Epididymis
- Exons
- Female
- Fertilization in Vitro
- Gene Deletion
- Genotype
- Humans
- Male
- Membrane Proteins
- Middle Aged
- Mutation
- Spermatozoa
- Time Factors
- Vas Deferens