Article
Cystic fibrosis mutation screening before assisted reproduction.
International journal of andrology - 1 Feb 2004
Gazvani R, Lewis-Jones D I
Abstract excerpt
Cystic fibrosis (CF) is the most common autosomal recessive disease in Caucasians, with a reported incidence of one in 2500. In 97-98% of men with CF, a congenital bilateral absence of the vas deferens (CBAVD) blocks the transport of spermatozoa from testicular or epididymal structures to the outer genital tract, resulting in azoospermia. Abnormalities in semen parameters have also been identified in males with...
Topics
- Cystic Fibrosis
- Genetic Counseling
- Genetic Testing
- Humans
- Incidence
- Male
- Mutation
- Oligospermia
- Reproductive Techniques, Assisted
- Vas Deferens