Article
[Donohue's syndrome (Leprechaunism)].
Nihon rinsho. Japanese journal of clinical medicine - 1 Oct 1994
Imamura T, Kobayashi M
Abstract excerpt
The syndrome of leprechaunism is characterized by the elfin-like face, hirsutism, acanthosis nigricans, absence of subcutaneous fat, and intrauterine and neonatal growth retardation. Most of the cases have severe insulin resistance with the mutation of the insulin receptor gene. In some cases, pa...
Topics
- Abnormalities, Multiple
- Acanthosis Nigricans
- Diabetes Mellitus
- Face
- Growth Disorders
- Hirsutism
- Humans
- Insulin Resistance
- Mutation
- Receptor, Insulin
- Syndrome