Article
Microbial evolution in a simple unstructured environment: genetic differentiation in Escherichia coli.
Genetics - 1 Aug 1994
Rosenzweig R F, Sharp R R, Treves D S, Adams J
Abstract excerpt
Populations of Escherichia coli initiated with a single clone and maintained for long periods in glucose-limited continuous culture, become polymorphic. In one population, three clones were isolated and by means of reconstruction experiments were shown to be maintained in stable polymorphism, although they exhibited substantial differences in maximum specific growth rates and in glucose uptake kinetics. Analysis...
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