Article
Mutation of dystrophin gene and cardiomyopathy.
Neuromuscular disorders : NMD - 1 Jul 1994
Nigro G, Politano L, Nigro V, Petretta V R, Comi L I
Abstract excerpt
The correlations between the type of gene mutation and the cardiac clinical picture were examined in 284 patients with dystrophinopathy (200 Duchenne and 84 Becker). The subjects with normal heart showed deletions including exons 48-49 in 21.4% DMD and in 25% BMD, and other deletions in 35.7% DMD and 25% BMD; vice versa the cases with severe cardiac involvement showed deletions including 48-49 in 38.8% DMD and...
Topics
- Adolescent
- Adult
- Aged
- Cardiomyopathies
- Child
- Child, Preschool
- Dystrophin
- Echocardiography
- Electrocardiography
- Gene Deletion
- Genes
- Genotype