Article
Genomic cloning and localization by FISH and linkage analysis of the human gene encoding the primary subunit NMDAR1 (GRIN1) of the NMDA receptor channel.
Annals of human genetics - 1 May 1994
Brett P M, Le Bourdelles B, See C G, Whiting P J, Attwood J, Woodward K, Robertson M M, Kalsi G, Povey S, Gurling H M
Abstract excerpt
A cDNA clone of the NMDAR1 (isoform E) has been used to screen both lambda and cosmid genomic libraries. A genomic phage clone was identified and sequenced and was found to contain some of the 3' coding regions of the GRIN1 gene. This clone was used to localize the gene using fluorescent in situ...
Topics
- Alleles
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 9
- Cloning, Molecular
- Female
- Genetic Linkage
- Genetic Markers
- Humans
- In Situ Hybridization, Fluorescence
- Male
- Minisatellite Repeats
- Polymerase Chain Reaction
- Receptors, N-Methyl-D-Aspartate