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Genetic Analysis of Childhood Endodermal Sinus Tumors by Comparative Genomic Hybridization

1 Mar 2000

Abstract excerpt

Childhood endodermal sinus tumors (CEST) are a distinct category of germ cell tumors that involve the testis and extragonadal sites of young children. Recurrent deletions of 1p and 6q have been reported by classic cytogenetic analysis of a small number of cases. Comparative genomic hybridization, a technique that screens the entire genome for genetic abnormalities, is applied to additionally define the genetic...

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PMID: 10779021
DOI: 10.1097/00043426-200003000-00003

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