Article
Systemic lupus erythematosus: considerations for a genetic approach.
The Journal of investigative dermatology - 1 Nov 1994
Harley J B, Sheldon P, Neas B, Murphy S, Wallace D J, Scofield R H, Shaver T S, Moser K L
Abstract excerpt
There is a powerful evidence suggesting that etiology and pathogenesis of systemic lupus erythematosus has both genetic and environmental components. Unfortunately, understanding the genetics of lupus has been impeded by knowing the pattern of inheritance. Indeed, a complex mode of inheritance fo...
Topics
- Alleles
- Animals
- Autoantibodies
- Autoimmunity
- Computer Simulation
- Environment
- Humans
- Lupus Erythematosus, Systemic
- Models, Genetic
- Pedigree