Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency.

doi:10.1016/s0021-9150(97)00093-2

Back to search

Article

Clinical characteristics of double heterozygotes with familial hypercholesterolemia and cholesteryl ester transfer protein deficiency.

Atherosclerosis - 25 Jul 1997

Haraki T, Inazu A, Yagi K, Kajinami K, Koizumi J, Mabuchi H

Abstract excerpt

Coronary heart disease (CHD) in familial hypercholesterolemia (FH) may be modified by genetic and/or environmental factors. We described the effect of the cholesteryl ester transfer protein (CETP) gene on CHD in heterozygous FH caused by low density lipoprotein receptor (LDL-R) gene mutation. In...

Topics

Adult
Carrier Proteins
Cholesterol Ester Transfer Proteins
Coronary Disease
Female
Glycoproteins
Heterozygote
Humans
Hyperlipoproteinemia Type II
Male
Middle Aged
Mutation
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.