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Article

US28: HCMV’s Swiss Army Knife

20 Aug 2018

Abstract excerpt

is one of four G protein coupled receptors (GPCRs) encoded by human cytomegalovirus (HCMV). The US28 protein (pUS28) is a potent signaling molecule that alters a variety of cellular pathways that ultimately alter the host cell environment. This viral GPCR is expressed not only in the context of lytic replication but also during viral latency, highlighting its multifunctional properties. pUS28 is a functional...

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PMID: 30127279
DOI: 10.3390/v10080445

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