Article
Molecular biology in radiation therapy: the potential impact of recombinant technology on clinical practice.
International journal of radiation oncology, biology, physics - 1 Dec 1994
Hall E J
Abstract excerpt
There is good evidence to believe that the most important lesion induced in deoxyribonucleic acid (DNA) by ionizing radiation is a double strand break. Two double strand breaks may interact and rejoin in three different ways. (a) To form a dicentric, which is a lethal event, and will lead to the...
Topics
- Amino Acid Sequence
- Animals
- DNA
- DNA, Recombinant
- Gamma Rays
- Genes, Suppressor
- Genetic Predisposition to Disease
- Genetic Techniques
- Humans
- Molecular Biology
- Molecular Sequence Data
- Multigene Family
- Neoplasms
- Neoplasms, Radiation-Induced
- Oncogenes
- Radiotherapy
- Transfection
- Translocation, Genetic