Pharmacogenetic characteristics of the eosinophilia-myalgia syndrome.

doi:10.1038/clpt.1994.154

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Article

Pharmacogenetic characteristics of the eosinophilia-myalgia syndrome.

Clinical pharmacology and therapeutics - 1 Oct 1994

Flockhart D A, Clauw D J, Sale E B, Hewett J, Woosley R L

Abstract excerpt

This study tested the hypothesis that patterns of xenobiotic metabolism in patients with eosinophilia-myalgia syndrome (EMS) differed from healthy control subjects. We determined the genotypes of 27 EMS patients with EMS and 114 control subjects for the cytochrome P450 CYP2D6 polymorphism. The me...

Topics

Alleles
Arylamine N-Acetyltransferase
Case-Control Studies
Dapsone
Debrisoquin
Eosinophilia-Myalgia Syndrome
Female
Genotype
Humans
Mephenytoin
Phenotype
Xenobiotics

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