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Article

Genetic determinants of metamizole metabolism modify the risk of developing anaphylaxis.

Pharmacogenetics and genomics - 1 Sept 2015

García-Martín Elena, Esguevillas Gara, Blanca-López Natalia, García-Menaya Jesús, Blanca Miguel, Amo Gemma, Canto Gabriela, Martínez Carmen, Cordobés Concepción, Agúndez José A G

Abstract excerpt

Metamizole is a NSAID that has been banned in several countries because of its toxicity. It is often involved in selective hypersensitivity reactions and most hypersensitivity patients develop anaphylaxis. Metamizole is rapidly metabolized, and metabolic profiles are related to genetic factors. We analyzed whether genetic determinants of metamizole metabolism influence the risk of developing hypersensitivity in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26111152
DOI: 10.1097/FPC.0000000000000157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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