Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells.

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Article

Retrovirus-mediated reconstitution of respiratory burst activity in X-linked chronic granulomatous disease cells.

Blood - 15 Nov 1994

Kume A, Dinauer M C

Abstract excerpt

X-linked chronic granulomatous disease (X-CGD) results from mutations in the gene encoding gp91phox, the larger subunit of the respiratory burst oxidase cytochrome b. In this study, a recombinant retrovirus vector was constructed and evaluated for its expression of human gp91phox in a human X-CGD...

Topics

Blotting, Northern
Cell Differentiation
Cell Line
Cell Membrane
Clone Cells
Cytochromes b5
Genetic Vectors
Granulocytes
Granulomatous Disease, Chronic
Humans
Membrane Glycoproteins
Mutation
NADPH Oxidase 2
NADPH Oxidases
Respiratory Burst
Retroviridae
Superoxides
Transfection

Source

Open in PubMed

Identifiers

PMID: 7949086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7949086-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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