Catalytic activity of anti-ground state antibodies, antibody subunits, and human autoantibodies.

doi:10.1007/BF02787938

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Article

Catalytic activity of anti-ground state antibodies, antibody subunits, and human autoantibodies.

Applied biochemistry and biotechnology - 1 Jan 2000

Paul S

Abstract excerpt

Catalytic antibodies may be produced over the natural course of antibody-affinity maturation by placement of chemically reactive residues in antibody-active sites by somatic hypermutation or V-D-J-gene rearrangement. This hypothesis has received support from recent observations on the chemical re...

Topics

Amino Acid Sequence
Antibodies, Anti-Idiotypic
Antibodies, Catalytic
Antigen-Antibody Reactions
Asthma
Autoantibodies
Chromatography, Affinity
DNA
Electrophoresis, Polyacrylamide Gel
Humans
Immunoglobulin G
Isoelectric Focusing
Molecular Sequence Data
Mutation
Vasoactive Intestinal Peptide

Source

Open in PubMed

Identifiers

PMID: 7944341
DOI: 10.1007/BF02787938

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7944341-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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