Article
Immunodeficiency-associated malignant lymphoma. Three cases showing genotypic evidence of both T- and B-cell lineages.
The American journal of surgical pathology - 1 Nov 1994
Hollingsworth H C, Stetler-Stevenson M, Gagneten D, Kingma D W, Raffeld M, Jaffe E S
Abstract excerpt
Dual rearrangement of both immunoglobulin and T-cell receptor (TCR) genes has been described in up to 30% of precursor lymphoid neoplasms, but this phenomenon occurs rarely in lymphomas with a mature phenotype. We describe three cases of immunodeficiency-associated lymphomas, two in patients with acquired immunodeficiency syndrome (AIDS) and one in a patient with a renal transplant, in which both immunoglobulin...
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