Article
Immunodeficiency-associated malignant lymphoma. Three cases showing genotypic evidence of both T- and B-cell lineages.
The American journal of surgical pathology - 1 Nov 1994
Hollingsworth H C, Stetler-Stevenson M, Gagneten D, Kingma D W, Raffeld M, Jaffe E S
Abstract excerpt
Dual rearrangement of both immunoglobulin and T-cell receptor (TCR) genes has been described in up to 30% of precursor lymphoid neoplasms, but this phenomenon occurs rarely in lymphomas with a mature phenotype. We describe three cases of immunodeficiency-associated lymphomas, two in patients with...
Topics
- Adult
- Blotting, Southern
- Child
- DNA Probes
- Female
- Gene Rearrangement, T-Lymphocyte
- Genotype
- Herpesviridae Infections
- Herpesvirus 4, Human
- Humans
- Immunocompromised Host
- Immunophenotyping
- In Situ Hybridization
- Lymphoma
- Lymphoma, AIDS-Related
- Lymphoma, B-Cell
- Lymphoma, T-Cell
- Male