Article
Frequent reinfection and reactivation of hepatitis C virus genotypes in multitransfused hemophiliacs.
The Journal of infectious diseases - 1 Oct 1994
Jarvis L M, Watson H G, McOmish F, Peutherer J F, Ludlam C A, Simmonds P
Abstract excerpt
The frequency and dynamics of infection with different genotypes of hepatitis C virus were investigated in a cohort of hemophiliacs repeatedly exposed to non-virus-inactivated clotting factor. Among 63 infected hemophiliacs, genotype 1 (n = 38, subtypes 1a [27] and 1b [11]) was predominant; genot...
Topics
- Blood Donors
- Blood Transfusion
- Enzyme-Linked Immunosorbent Assay
- Genotype
- Hemophilia A
- Hemophilia B
- Hepacivirus
- Hepatitis C
- Humans
- Polymerase Chain Reaction
- RNA, Viral
- Recurrence
- Restriction Mapping
- Virus Activation
