Article
Hepatitis C virus long-term persistence in peripheral blood mononuclear cells in patients with haemophilia. Detection of occult genotype 1.
Journal of viral hepatitis - 1 Jul 2015
Parodi C, García G, Monzani M C, Culasso A, Aloisi N, Corti M, Campos R, de E de Bracco M M, Baré P
Abstract excerpt
Peripheral blood mononuclear cells (PBMC) from chronic hepatitis C virus-infected persons can harbour viral variants that are not detected in plasma samples. We explored the presence and persistence of HCV genotypes in plasma and PBMC cultures from 25 HCV-monoinfected and 25 HIV/HCV-coinfected patients with haemophilia. Cell cultures were performed at different time points between 1993 and 2010-2011, and the HCV...
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