HLA-DQB1*0305 and -DQB1*0304 alleles among Sardinians. Evolutionary and practical implications for oligotyping.

doi:10.1016/0198-8859(94)90060-4

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Article

HLA-DQB10305 and -DQB10304 alleles among Sardinians. Evolutionary and practical implications for oligotyping.

Human immunology - 1 Jun 1994

Cucca F, Frau F, Lampis R, Floris M, Argiolas L, Macis D, Cao A, De Virgiliis S, Congia M

Abstract excerpt

This study, performed in individuals of Sardinian descent, reports an epidemiologic and molecular analysis of the recently identified DQB1*0304 and DQB1*0305 alleles. These two alleles having a gene frequency of 0.017 and 0.005, respectively, are not uncommon in Sardinia and are distributed fairl...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Exons
Gene Frequency
HLA-DQ Antigens
HLA-DQ beta-Chains
Haplotypes
Humans
Infant, Newborn
Italy
Molecular Sequence Data
Thalassemia

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