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Article

First Report of the Rare IVS-II-705 (T>G) β-Thalassemia Mutation in a Chinese Family.

Hemoglobin - 1 Jan 2000

Jiang Fan, Chen Gui-Lan, Zhou Jian-Ying, Li Dong-Zhi

Abstract excerpt

We have found an example of the mutation at the intronic region of the second intervening sequence of the β-globin gene, IVS-II-705 (T>G) (HBB: c.316-146T>G), in a Chinese family. The two subjects heterozygous for this mutation presented with typical β-thalassemia (β-thal) trait.

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Source

Identifiers

PMID: 29251008
DOI: 10.1080/03630269.2017.1408647

Genes

HBB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

First Report of the Rare IVS-II-705 (T>G) β-Thalassemia Mutation in a Chinese Family.PMID 29251008Read ↗

First Detection of a Splice Site β-Thalassemia Mutation, IVS-I-6 (T > C) (HBB: c.92 + 6T > C) in a Chinese Family.Semantic proximity Read ↗

A novel beta-thalassemia mutation [IVS-II-5 (G-->C)] in a Chinese family from Guangxi Province, P.R. China.Semantic proximity Read ↗

First Detection of a Splice Acceptor Site β-Thalassemia Mutation: IVS-I-130 (HBB: c.93-1G > C) in a Chinese Patient.Semantic proximity Read ↗

Two novel beta-thalassemia alleles in the Chinese: the IVS-II-2 (-T) and nucleotide +8 (C-->T) beta-globin gene mutations.Semantic proximity Read ↗

A common Chinese beta-thalassemia mutation found in a Japanese family.Semantic proximity Read ↗

A Novel β-Thalassemia Mutation [IVS-I-6 (T>G), HBB: c.92+6T>G] in a Chinese Family.Semantic proximity Read ↗

Another example of the beta-thalassemia mutation, IVS-I (-2) or codon 30 (A-->G), found in a Chinese family.Semantic proximity Read ↗

First Detection of the -27 (A > G) (HBB: c.-77A > G) Mutation of the β-Globin Gene in a Chinese Family.Semantic proximity Read ↗

First Description of a β-Thalassemia Mutation, -86 (C > G) (HBB: c.-136C > G), in a Chinese Family.Semantic proximity Read ↗

Dominantly Inherited β-Thalassemia Caused by a Single Nucleotide Deletion in Exon 3 of the β-Globin Gene: Hb Xiangyang (HBB: c.393delT).Semantic proximity Read ↗

Molecular basis and haematological characterization of beta-thalassaemia major in Taiwan, with a mutation of IVS-1 3' end TAG-->GAG in a Chinese patient.Semantic proximity Read ↗

Identification of a Novel Mutation in the 3' Untranslated Region of the β-Globin Gene (HBB:c.*132C>G) in a Chinese Family.Semantic proximity Read ↗

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