Article
Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification.
Blood - 1 Oct 1994
Hébert J, Cayuela J M, Daniel M T, Berger R, Sigaux F
Abstract excerpt
Acute myelomonocytic leukemia with bone marrow eosinophilia (AML-M4Eo in the French-American-British FAB] classification) is frequently associated with pericentric inversion of chromosome 16, inv(16)(p13q22). Recently, the molecular cloning of teh breakpoints has led to the identification of the two fused genes, CBFB on 16q and MYH11 on 16p. We have analyzed 24 patients with AML-M4Eo at diagnosis and 47 patients...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.