Article
Detection of minimal residual disease in acute myelomonocytic leukemia with abnormal marrow eosinophils by nested polymerase chain reaction with allele specific amplification.
Blood - 1 Oct 1994
Hébert J, Cayuela J M, Daniel M T, Berger R, Sigaux F
Abstract excerpt
Acute myelomonocytic leukemia with bone marrow eosinophilia (AML-M4Eo in the French-American-British FAB] classification) is frequently associated with pericentric inversion of chromosome 16, inv(16)(p13q22). Recently, the molecular cloning of teh breakpoints has led to the identification of the...
Topics
- Alleles
- Base Sequence
- Chromosome Inversion
- Chromosomes, Human, Pair 16
- DNA Primers
- Eosinophils
- Humans
- Leukemia, Myelomonocytic, Acute
- Molecular Sequence Data
- Myosins
- Neoplasm, Residual
- Polymerase Chain Reaction
- RNA, Neoplasm
- Recombinant Fusion Proteins
- Transcription Factors