Article
Molecular analysis of Polish patients with factor VII deficiency.
Blood - 1 Oct 1994
Arbini A A, Bodkin D, Lopaciuk S, Bauer K A
Abstract excerpt
We analyzed the mutations in patients from 10 Polish kindreds with a bleeding diathesis due to factor VII deficiency. Patients from eight families had plasma levels of factor VII coagulant activity (VII:C) and factor VII antigen (VII:Ag) that were less than 4% of normal. The coding sequence of th...
Topics
- Alleles
- Base Sequence
- DNA Primers
- Factor VII
- Factor VII Deficiency
- Female
- Humans
- Male
- Molecular Sequence Data
- Mutation
- Pedigree
- Poland
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational
- Sequence Deletion