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Article

Analysis of the functional effects of a mutation in SOD1 associated with familial amyotrophic lateral sclerosis.

Neuron - 1 Sept 1994

Tsuda T, Munthasser S, Fraser P E, Percy M E, Rainero I, Vaula G, Pinessi L, Bergamini L, Vignocchi G, McLachlan D R

Abstract excerpt

Mutations in the Cu, Zn superoxide dismutase (SOD1) gene have been reported in some pedigrees with Familial Amyotrophic Lateral Sclerosis (FALS). We have investigated the functional and structural effects of a Gly-->Ser mutation at codon 41 of SOD1 in a pedigree with FALS and the topography of SO...

Topics

Amino Acid Sequence
Amyotrophic Lateral Sclerosis
Animals
Base Sequence
Immunohistochemistry
In Situ Hybridization
Male
Molecular Biology
Molecular Probes
Molecular Sequence Data
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats

Rats, Sprague-Dawley

Superoxide Dismutase

Source

Identifiers

PMID: 7917302
DOI: 10.1016/0896-6273(94)90039-6

Genes

SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7917302-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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