Article
Genetic analysis of the brahma gene of Drosophila melanogaster and polytene chromosome subdivisions 72AB.
Genetics - 1 Jul 1994
Brizuela B J, Elfring L, Ballard J, Tamkun J W, Kennison J A
Abstract excerpt
The brahma gene is required for activation of the homeotic genes of the Antennapedia and bithorax complexes in Drosophila. We have isolated and characterized 21 mutations in brahma. We show that both maternal and zygotic functions of brahma are required during embryogenesis. In addition, the severe abnormalities caused by loss of maternal brahma expression show that the homeotic genes are not the only targets for...
Topics
- ADP-Ribosylation Factors
- Alleles
- Animals
- Blotting, Northern
- Cell Cycle Proteins
- Chromosome Mapping
- Crosses, Genetic
- Drosophila Proteins
- Drosophila melanogaster
- Embryonic Development
- Epistasis, Genetic