Polymorphism of the tumor necrosis factor genes in patients with dermatitis herpetiformis.

doi:10.1159/000246957

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Article

Polymorphism of the tumor necrosis factor genes in patients with dermatitis herpetiformis.

Dermatology (Basel, Switzerland) - 1 Jan 1994

Messer G, Kick G, Ranki A, Koskimies S, Reunala T, Meurer M

Abstract excerpt

In 18 patients with dermatitis herpetiformis (DH) of whom 16 were HLA-DR3 positive and 14 had the HLA-B8, -DR3 haplotype, the frequencies of known mutations of the tumor necrosis factor alpha (TNF-alpha) and TNF-beta genes were investigated using restriction fragment length polymorphism analysis...

Topics

Alleles
Dermatitis Herpetiformis
HLA Antigens
Humans
Lymphotoxin-alpha
Phenotype
Polymerase Chain Reaction
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Tumor Necrosis Factor-alpha

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