Article
Molecular characterization of the HLA-DR2LUM haplotype.
Tissue antigens - 1 Jan 1994
Young N T, Darke C
Abstract excerpt
Molecular studies of HLA-DRB, -DRA and -DQB1 genes in the variant DR2 haplotype, DR2LUM, were performed using the homozygous lymphoblastoid cell line, CTS. The results of HLA Class II gene RFLP and PCR analyses suggest that DR2LUM was created by a homologous recombination event between HLA-DR1 an...
Topics
- Alleles
- Base Sequence
- Cell Line
- DNA
- DNA Probes
- HLA-DR2 Antigen
- Haplotypes
- Humans
- Lymphocytes
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length