Article
"RFLP subtraction": a method for making libraries of polymorphic markers.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994
Rosenberg M, Przybylska M, Straus D
Abstract excerpt
We developed a method, "RFLP subtraction," that isolates large numbers of unique sequence restriction fragment length polymorphisms (RFLPs) in a single experiment. The technique purifies small restriction fragments from one genome containing sequences that reside on large fragments in a related g...
Topics
- Alleles
- Animals
- Base Sequence
- Cloning, Molecular
- DNA
- Deoxyribonuclease HindIII
- Gene Library
- Genetic Markers
- Genetic Techniques
- Genome
- Lod Score
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Oligodeoxyribonucleotides
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Polymorphism, Restriction Fragment Length