Article
"RFLP subtraction": a method for making libraries of polymorphic markers.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994
Rosenberg M, Przybylska M, Straus D
Abstract excerpt
We developed a method, "RFLP subtraction," that isolates large numbers of unique sequence restriction fragment length polymorphisms (RFLPs) in a single experiment. The technique purifies small restriction fragments from one genome containing sequences that reside on large fragments in a related genome. We first isolate samples containing the small restriction fragments from two polymorphic strains. Subtractive...
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