Article
A comparison of the allelic frequencies of ten DNA polymorphisms associated with factor VIII and factor IX genes in Thai and Western European populations.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Feb 1994
Goodeve A C, Chuansumrit A, Sasanakul W, Isarangkura P, Preston F E, Peake I R
Abstract excerpt
The frequency of five factor VIII gene intragenic and linked DNA polymorphisms and five factor IX gene intragenic polymorphisms was studied in Thai females. The polymorphisms in the FVIII gene were detected by restriction enzymes BclI, XbaI, BglI and at linked loci DX13 (DXS15) and St14 (DXS52) by BglII and TaqI, respectively, and in the FIX gene by MseI, DdeI, XmnI, TaqI and HhaI. With the exception of the BglI...
Topics
- Alleles
- Bacterial Proteins
- Deoxyribonucleases, Type II Site-Specific
- Europe
- Factor IX
- Factor VIII
- Female
- Gene Frequency
- Genetic Carrier Screening
- Hemophilia A