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Article

Alzheimer's disease and Creutzfeldt-Jakob disease: overlap of pathogenic mechanisms.

Current opinion in neurology - 1 Dec 1993

DeArmond S J

Abstract excerpt

This article compares beta-amyloid precursor protein (beta-APP) disorders exemplified by Alzheimer's disease (AD), with prion protein (PrP) disorders, exemplified by Creutzfeldt-Jakob disease (CJD) in humans and scrapie in animals. Although there are obvious differences in the etiology and pathogenesis of both sets of disorders, a remarkable number of similarities exist. Both sets of disorders are characterized...

Topics

Aged
Alzheimer Disease
Amyloid beta-Protein Precursor
Animals
Brain
Creutzfeldt-Jakob Syndrome
Disease Models, Animal
Humans
Mutation
PrPSc Proteins
Prions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7904883
DOI: 10.1097/00019052-199312000-00008

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7904883-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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