Article
Alzheimer's disease and Creutzfeldt-Jakob disease: overlap of pathogenic mechanisms.
Current opinion in neurology - 1 Dec 1993
DeArmond S J
Abstract excerpt
This article compares beta-amyloid precursor protein (beta-APP) disorders exemplified by Alzheimer's disease (AD), with prion protein (PrP) disorders, exemplified by Creutzfeldt-Jakob disease (CJD) in humans and scrapie in animals. Although there are obvious differences in the etiology and pathogenesis of both sets of disorders, a remarkable number of similarities exist. Both sets of disorders are characterized...
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