Article
Genetic homogeneity in Sjögren-Larsson syndrome: linkage to chromosome 17p in families of different non-Swedish ethnic origins.
American journal of human genetics - 1 Nov 1995
Rogers G R, Rizzo W B, Zlotogorski A, Hashem N, Lee M, Compton J G, Bale S J
Abstract excerpt
Sjögren-Larsson syndrome (SLS) is a rare, autosomal recessive disorder that is characterized by congenital ichthyosis, mental retardation, and spastic diplegia or tetraplegia. Three United States families, three Egyptian families, and one Israeli Arab family were investigated for linkage of the SLS gene to a region of chromosome 17. Pairwise and multipoint linkage analysis with nine markers mapped the SLS gene to...
Topics
- Alleles
- Chromosome Mapping
- Chromosomes, Human, Pair 17
- Genetic Linkage
- Haplotypes
- Humans
- Lod Score
- Pedigree
- Sjogren-Larsson Syndrome
- Sweden