Article
[Initial Dutch results with a presymptomatic DNA tests in familial breast/ovarian carcinoma. Rotterdamse Werkgroep voor Erfelijke Tumoren].
Nederlands tijdschrift voor geneeskunde - 4 Mar 1995
Klijn J G, Devilee P, van Geel A N, Tilanus-Linthorst M M, Dudok-de Wit C, Meijers-Heijboer E J
Abstract excerpt
Recent discoveries in the field of molecular-genetic research make it possible to detect an increased genetic risk of tumours, because several genes are linked to hereditary forms of breast cancer. The breast cancer gene BRCA1, located on chromosome 17q, is quantitatively the most important gene...
Topics
- Adult
- Aged
- Breast Neoplasms
- DNA, Neoplasm
- Decision Making
- Female
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Middle Aged
- Mutation
- Ovarian Neoplasms
- Pedigree
