The role of histidine residues in the catalytic act of cyclomaltodextrin glucanotransferase from Bacillus circulans var. alkalophilus.

doi:10.1016/0167-4838(94)00214-2

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Article

The role of histidine residues in the catalytic act of cyclomaltodextrin glucanotransferase from Bacillus circulans var. alkalophilus.

Biochimica et biophysica acta - 22 Feb 1995

Mattsson P, Battchikova N, Sippola K, Korpela T

Abstract excerpt

Our previous study on cyclomaltodextrin glucanotransferase (CGTase) by chemical modification implied the importance of one or two histidine residues in the cyclization reaction of the enzyme. Based on a computer modelled three-dimensional structure of the CGTase, five histidine residues were chos...

Topics

Bacillus
Base Sequence
Binding Sites
Glucosyltransferases
Histidine
Molecular Sequence Data
Mutagenesis, Site-Directed
Mutation
Polymerase Chain Reaction

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