Article
Failure to detect Trichinella spiralis p43 in isolated host nuclei and in irradiated larvae of infected muscle cells which express the infected cell phenotype.
Molecular and biochemical parasitology - 1 Oct 1994
Jasmer D P, Yao S, Vassilatis D, Despommier D, Neary S M
Abstract excerpt
Infection by Trichinella spiralis induces host muscle cells to become repositioned within the cell cycle and to lose differentiated skeletal muscle characteristics. Antibodies to a 43-kDa excretory-secretory (ES) protein (p43) also bind to infected host cell nuclei. Neither the identity of these...
Topics
- Animals
- Antibodies, Helminth
- Antigens, Helminth
- Blotting, Western
- Cell Nucleus
- Cell Separation
- Fluorescent Antibody Technique
- Helminth Proteins
- Larva
- Mice
- Muscle, Skeletal
- Nuclear Proteins