Article
Human diseases with defects in oxidative phosphorylation. 1. Decreased amounts of assembled oxidative phosphorylation complexes in mitochondrial encephalomyopathies.
European journal of biochemistry - 1 Feb 1995
Bentlage H, de Coo R, ter Laak H, Sengers R, Trijbels F, Ruitenbeek W, Schlote W, Pfeiffer K, Gencic S, von Jagow G
Abstract excerpt
The amount of oxidative phosphorylation enzymes in mitochondrial encephalomyopathy patients has been studied by two-dimensional electrophoresis (blue native PAGE/Tricine-SDS-PAGE). Only 20 mg muscle was required to identify and analyse complexes I, III, IV, and V after Coomassie staining. In most...
Topics
- Adult
- Child
- Child, Preschool
- DNA, Mitochondrial
- Electrophoresis, Gel, Two-Dimensional
- Female
- Humans
- In Vitro Techniques
- Infant, Newborn
- Male
- Mitochondrial Encephalomyopathies