Article
Molecular analysis of a leu2-mutant of Candida maltosa demonstrates the presence of multiple alleles.
Current genetics - 1 Sept 1994
Becher D, Schulze S, Kasüske A, Schulze H, Samsonova I A, Oliver S G
Abstract excerpt
Three different alleles of the beta-isopropylmalate dehydrogenase gene were cloned and sequenced from a leucine auxotrophic mutant, G587, of Candida maltosa. The cloning of functionally-intact wild-type genes from this mutant strain suggests the presence of silent gene copies. An interallelic-div...
Topics
- 3-Isopropylmalate Dehydrogenase
- Alcohol Oxidoreductases
- Alleles
- Amino Acid Sequence
- Base Sequence
- Blotting, Southern
- Candida
- Cloning, Molecular
- DNA, Fungal
- Genes, Fungal
- Genetic Complementation Test
- Genetic Variation
- Karyotyping
- Leucine
- Molecular Sequence Data
- Mutagenesis
- Plasmids
- Ploidies