Article
Molecular analysis of a leu2-mutant of Candida maltosa demonstrates the presence of multiple alleles.
Current genetics - 1 Sept 1994
Becher D, Schulze S, Kasüske A, Schulze H, Samsonova I A, Oliver S G
Abstract excerpt
Three different alleles of the beta-isopropylmalate dehydrogenase gene were cloned and sequenced from a leucine auxotrophic mutant, G587, of Candida maltosa. The cloning of functionally-intact wild-type genes from this mutant strain suggests the presence of silent gene copies. An interallelic-divergence comparison has provided evidence for new regulatory mechanisms. Sequence data and karyotype analysis argue for...
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