Article
Expression and genomic configuration of GM-CSF, IL-3, M-CSF receptor (C-FMS), early growth response gene-1 (EGR-1) and M-CSF genes in primary myelodysplastic syndromes.
Leukemia & lymphoma - 1 Sept 1994
Mareni C, Sessarego M, Montera M, Fugazza G, Origone P, D'Amato E, Lerza R, Pistoia V, Scarra G B
Abstract excerpt
Peripheral blood mononuclear cells from seventeen patients with primary myelodysplastic syndromes (MDS) in advanced stage were enriched for blasts and tested for (1) karyotype, (2) genomic configuration and (3) expression of IL-3, GM-CSF, FMS and EGR-1 genes which are all located on the long arm...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Chromosome Aberrations
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 5
- DNA-Binding Proteins
- Early Growth Response Protein 1
- Female
- Fibroblasts
- Gene Expression Regulation
- Genes
- Granulocyte-Macrophage Colony-Stimulating Factor