Article
Genomic organization and chromosomal assignment of the human voltage-gated Na+ channel beta 1 subunit gene (SCN1B).
Genomics - 1 Oct 1994
Makita N, Sloan-Brown K, Weghuis D O, Ropers H H, George A L
Abstract excerpt
Voltage-gated sodium (Na+) channels are essential for the generation and propagation of action potentials in striated muscle and neuronal tissues. Biochemically, Na+ channels consist of a large alpha subunit and one or two smaller beta subunits. The alpha subunit alone can exhibit all of the func...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 19
- Consensus Sequence
- DNA
- DNA Primers
- Exons
- Genomic Library
- Hominidae
- Humans
- In Situ Hybridization, Fluorescence
- Introns
- Macromolecular Substances
- Molecular Sequence Data
- Muscles