Article
Methionine-321 in the C-terminal alpha-helix of catabolic ornithine carbamoyltransferase from Pseudomonas aeruginosa is important for positive homotropic cooperativity.
FEMS microbiology letters - 15 Dec 1994
Nguyen V T, Tricot C, Stalon V, Dideberg O, Villeret V, Haas D
Abstract excerpt
Pseudomonas aeruginosa has a pair of distinct ornithine carbamoyltransferases. The anabolic ornithine carbamoyltransferase encoded by the argF gene catalyzes the formation of citrulline from ornithine and carbamoylphosphate. The catabolic ornithine carbamoyltransferase encoded by the arcB gene pr...
Topics
- Allosteric Regulation
- Animals
- Enzyme Activation
- Methionine
- Mutation
- Ornithine Carbamoyltransferase
- Plasmids
- Protein Structure, Secondary
- Pseudomonas aeruginosa