Article
Incidence of the apolipoprotein B-3500 mutation in Denmark.
Clinica chimica acta; international journal of clinical chemistry - 14 Oct 1994
Hansen P S, Nørgaard-Petersen B, Meinertz H, Jensen H K, Hansen A B, Klausen I C, Gerdes L U, Faergeman O
Abstract excerpt
A total of 5000 consecutively samples newborn screening cards were anonymously selected for screening for the apolipoprotein B-3500 (apo B-3500) mutation, which causes familial defective apolipoprotein B-100 (FDB). The mutation was found in 5 of 5000 Danish children, of whom 2 were twins. This indicates a lower prevalence of this mutation in Danes than that reported in the UK, Germany, USA, Austria, Canada and...
Topics
- Apolipoproteins B
- DNA Mutational Analysis
- Denmark
- Heterozygote
- Humans
- Hypercholesterolemia
- Infant, Newborn
- Mutation
- Neonatal Screening
- Polymerase Chain Reaction