Article
The tuberous sclerosis gene on chromosome 9q34 acts as a growth suppressor
1 Jan 1994
Abstract excerpt
We have previously demonstrated allele loss in hamartomas from patients with tuberous sclerosis for markers spanning the tuberous sclerosis gene on chromosome 16q13.3 (TSC2). Germline deletions in the TSC2 gene have been shown in 5% of patients with tuberous sclerosis (TSC). These data support our hypothesis that the TSC2 gene acts as a growth suppressor gene, analogous to the traditional tumour suppressor gene....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.