Article
The molecular genetics of familial venous thrombosis.
Bailliere's clinical haematology - 1 Sept 1994
Cooper D N
Abstract excerpt
This study of naturally occurring mutations predisposing to venous thrombosis has led to a number of important advances in our understanding of protein structure and function relationships and the molecular basis of gene mutation. It has also potentiated the accurate and reliable presymptomatic and antenatal detection of predisposing gene lesions. Perhaps the major challenge facing us is the probabilistic nature...
Topics
- Afibrinogenemia
- Amino Acid Sequence
- Antithrombin III
- Antithrombin III Deficiency
- Base Sequence
- DNA Mutational Analysis
- Fibrinogens, Abnormal
- Genes
- Genetic Predisposition to Disease
- Humans
- Lipoprotein(a)