Article
Tissue-specific and developmentally regulated alternative splicing in mouse skeletal muscle ryanodine receptor mRNA.
The Biochemical journal - 15 Jan 1995
Futatsugi A, Kuwajima G, Mikoshiba K
Abstract excerpt
The ryanodine receptor is a channel for Ca2+ release from intracellular stores. By PCR analysis, we identified two alternatively spliced regions in mRNA of the mouse skeletal muscle ryanodine receptor (sRyR). The splice variants were characterized by the presence or absence of 15 bp (ASI) and 18...
Topics
- Alternative Splicing
- Amino Acid Sequence
- Animals
- Base Sequence
- Brain
- Calcium Channels
- Exons
- Genetic Variation
- Introns
- Mice
- Mice, Inbred ICR
- Molecular Sequence Data
- Muscle Development
- Muscle Proteins
- Muscle, Skeletal
- RNA, Messenger
- Ryanodine Receptor Calcium Release Channel
- Time Factors