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Article

Tissue-specific and developmentally regulated alternative splicing in mouse skeletal muscle ryanodine receptor mRNA.

The Biochemical journal - 15 Jan 1995

Futatsugi A, Kuwajima G, Mikoshiba K

Abstract excerpt

The ryanodine receptor is a channel for Ca2+ release from intracellular stores. By PCR analysis, we identified two alternatively spliced regions in mRNA of the mouse skeletal muscle ryanodine receptor (sRyR). The splice variants were characterized by the presence or absence of 15 bp (ASI) and 18 bp (ASII) exons. The exclusion of these exons results in the absence of the regions corresponding to Ala3481-Gln3485...

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Identifiers

PMID: 7832748
DOI: 10.1042/bj3050373
PMCID: PMC1136371

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