Article
Extracellular matrix proteins, integrin receptors (VLA-beta 1, VLA-alpha 2 and VLA-alpha 5) and growth fraction in atypical macroregenerative nodules of the liver: an immunocytochemical case study.
Histochemistry - 1 Aug 1994
Patriarca C, Roncalli M, Viale G, Alfano R M, Braidotti P, Guddo F, Coggi G
Abstract excerpt
A case of cirrhotic liver harbouring three atypical macroregenerative nodules and an hepatocellular carcinoma was immunocytochemically investigated for the expression of VLA-beta 1, VLA-alpha 2 and VLA-alpha 5 integrins and for different extracellular matrix (ECM) components (collagen I, collagen IV, laminin, fibronectin and tenascin). In addition, the proliferative activity within the nodules was evaluated,...
Topics
- Carcinoma, Hepatocellular
- Cell Adhesion Molecules
- Cell Division
- Extracellular Matrix Proteins
- Humans
- Immunohistochemistry
- Integrins
- Liver Cirrhosis
- Liver Neoplasms
- Liver Regeneration