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Article

Molecular cloning and derived primary structure of cobra venom factor.

20 Dec 1994

Abstract excerpt

Cobra venom factor (CVF) is the complement-activating protein in cobra venom. Like C3b, CVF forms with factor B and factor D in human and mammalian serum the bimolecular C3/C5 convertase. This functional similarity of CVF and C3 correlates with many structural similarities, which led to the suggestion that CVF is evolutionally related to C3. We report here the molecular cloning and derived primary structure of...

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PMID: 7809120
DOI: 10.1073/pnas.91.26.12775

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