Article
Mini-exon gene variation in human pathogenic Leishmania species.
Molecular and biochemical parasitology - 1 Aug 1994
Fernandes O, Murthy V K, Kurath U, Degrave W M, Campbell D A
Abstract excerpt
We have used polymerase chain reaction to amplify the mini-exon gene repeat from 18 Leishmania strains. DNA sequence analysis of the cloned products reveals high conservation of both the exon and intron (i.e. transcribed region). In contrast, variation is evident in both the length and primary se...
Topics
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Primers
- DNA, Protozoan
- Exons
- Gene Rearrangement
- Genes, Protozoan
- Genetic Variation
- Humans
- Introns
- Leishmania
- Molecular Sequence Data
- Polymerase Chain Reaction
- Recombination, Genetic
- Repetitive Sequences, Nucleic Acid
- Sequence Deletion
- Sequence Homology, Nucleic Acid