Article
Multi-site DNA polymorphism analyses of Leishmania isolates define their genotypes predicting clinical epidemiology of leishmaniasis in a specific region.
The Journal of eukaryotic microbiology - 1 Jan 2000
Akman L, Aksu H S, Wang R Q, Ozensoy S, Ozbel Y, Alkan Z, Ozcel M A, Culha G, Ozcan K, Uzun S, Memisoglu H R, Chang K P
Abstract excerpt
Leishmania isolates from 57 cases of human cutaneous (CL), human visceral (VL), and canine visceral (CVL) leishmaniasis in Turkey were grouped by multi-site DNA polymorphism analyses into five genotypes. The initial grouping was based on DNA heterogeneity of the faster-evolving mitochondrion (kinetoplast) minicircles and the intergenic regions of two nuclear repetitive genes. Taxonomic affiliation and...
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