Article
Caenorhabditis elegans sqt-3 mutants have mutations in the col-1 collagen gene.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Sept 1994
van der Keyl H, Kim H, Espey R, Oke C V, Edwards M K
Abstract excerpt
sqt-3 mutants of Caenorhabditis elegans form dumpy larvae and adults and display allele-specific defects in locomotion, fertility, and viability. We have determined that the sqt-3 locus encodes COL-1 collagen. We physically mapped the col-1 gene to a cosmid on chromosome V whose position is consi...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Chromosome Mapping
- Cloning, Molecular
- Collagen
- Gene Expression Regulation, Developmental
- Genes, Helminth
- Molecular Sequence Data
- Phenotype
- Point Mutation
- Sequence Analysis, DNA
- Temperature