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Article

Cloning of a putative human voltage-gated chloride channel (CIC-2) cDNA widely expressed in human tissues

1 Jan 1995

Abstract excerpt

We have cloned a cDNA from the human epithelial cell line T84 whose predicted amino acid sequence shows 93.9% identity with rat CIC-2. Mapping by somatic cell hybrids and polymerase chain reaction localizes the gene corresponding to this cDNA to chromosome 3q26-qter. The major transcription start site assessed by RNA primer extension is 100 nt upstream of the putative translation initiation codon. Analysis of the...

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PMID: 7795595
DOI: 10.1093/hmg/4.3.407

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