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Article

Genomic structure and functional expression of a human alpha(2)/delta calcium channel subunit gene (CACNA2).

Genomics - 15 Oct 1999

Schleithoff L, Mehrke G, Reutlinger B, Lehmann-Horn F

Abstract excerpt

CACNA2 encodes the alpha(2)/delta subunit of the human voltage-gated calcium channels and is located in the candidate region of malignant hyperthermia susceptibility type 3 (MHS3). We determined the structural organization of CACNA2 by isolation of overlapping genomic DNA clones from a human phage library. The gene consists of at least 40 exons, 2 of which are alternatively spliced, spanning more than 150 kb of...

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Identifiers

PMID: 10534405
DOI: 10.1006/geno.1999.5941

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