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Article

Highly polymorphic sequence at D21S1448 mapping close to D21S55, within the Down syndrome critical region.

Human genetics - 1 Jun 1995

Hernandez D, Pannett A A, Tybulewicz V, Fisher E M

Abstract excerpt

We have isolated a highly polymorphic sequence from the Down syndrome critical region on human chromosome 21. This is a particularly useful marker because it lies adjacent to the locus D21S55, which is most closely associated with the major defects on Down syndrome. Other than this marker, few other variable sequences are known in this region (including other restriction fragment length polymorphisms or CA...

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PMID: 7789964
DOI: 10.1007/BF00209498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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